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This allergic response is often existence-threatening and may cause Loss of life. Connect with your healthcare provider right away When you have: a pores and skin rash, hives; fever or swollen glands that do not go away; swelling of your face; shortness of breath; swelling of your legs; yellowing from the skin or whites from the eyes; or darkish urine The commonest Unwanted side effects of FYCOMPA contain:

saquinavir will enhance the level or influence of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

modafinil will raise the degree or outcome of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Sturdy or average CYP2C19 inhibitors may possibly raise mavacamten systemic publicity, causing heart failure resulting from systolic dysfunction.

Provigil is employed to take care of extreme sleepiness attributable to slumber apnea, narcolepsy, or shift get the job done sleep dysfunction.

The proposed dosage of PROVIGIL for people with SWD is two hundred mg taken orally as soon as daily as one dose somewhere around 1 hour just before the beginning of their get the job done change.

Doses as much as 400 mg/day, provided as a single dose, happen to be effectively tolerated, but there is no dependable proof this dose confers supplemental profit outside of that from the 200 mg/day dose

Stay away from or substitute another drug for these prescription drugs when possible. Consider for lack of therapeutic result if medication must be coadministered. Modify dose In keeping with prescribing data if required.

The equal armodafinil dosage With this array can be 50 mg but could be marginally more powerful in its consequences.

modafinil will enhance the amount or website result of rabeprazole by affecting hepatic enzyme CYP2C19 metabolism. Minor/Importance Mysterious. Net impact on pantoprazole steps unidentified on account of opposing consequences of CYP450 enzymes; observe

Modafinil is often a white to off-white, crystalline powder that's virtually insoluble in drinking water and cyclohexane. It really is sparingly to marginally soluble in methanol and acetone.

Modafinil appeared to make a concentration-associated suppression of CYP2C9 activity, hence suggesting probable for CYP2C9 inhibition; caution if medicines that have a slender therapeutic index

In situations wherever continuous good airway strain (CPAP) is definitely the treatment of choice for extreme sleepiness, a maximal hard work to deal with with CPAP for an suitable period of time ought to be created just before initiating this drug.

Minimal (one)modafinil will increase the level or impact of lansoprazole by impacting hepatic enzyme CYP2C19 metabolism. Slight/Importance Mysterious. Web impact on pantoprazole actions unfamiliar on account of opposing outcomes of CYP450 enzymes; watch